The spleen normally lies along the long axis of the 10th rib. Its lower pole extends forward as far as the midaxillary line.

Causes of splenomegaly include:

Diseases in which splenomegaly if present is most likely to be massive are:

However, the commonest cause of massive splenomegaly in a large study in America was chronic liver disease. 



grecian treasure said...

In subcontinent the tropical splenomegaly or hypermalarial syndrome as a cause of massive splenomegaly is also very common.

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